“Researchers found that if you’re not getting sufficient sleep in the week before you get your standard flu shot, you produce less than 50% of the normal antibody response, rendering that vaccination far less effective.”

https://www.bbc.co.uk/news/world-53082182?fbclid=IwAR355JUPh4s9xd1GT-kBxb1rP1y5sWWBOLT-NhmZm2snziiS_Wqk3rB31iM